Two characters from the original cast were eventually replaced with Clive Hornby taking over from Andrew Burt in 1980 and Debbi Blythe taking over from Gail Harrison for a short recurring period in 1987.
Of the original cast seen in the first episode in 1972, only Sheila Mercier, Andrew Burt, Frazer Hines, Frederick Pyne, Jo Kendall and Gail Harrison are still alive and of those, only Frazer Hines character (Joe Sugden) and Jo Kendall's character (Peggy Skilbeck) have been killed off in the show.
|Character||Actor||When they left|
|Annie Sugden||Sheila Mercier||2009|
|Jack Sugden||Clive Hornby (1980 onwards)|
Andrew Burt (until 1976)
|2008 (recurring until 1980)|
|Joe Sugden||Frazer Hines||1994|
|Amos Brearly||Ronald Magill||1992 (recurring until 1995)|
|Henry Wilks||Arthur Pentelow||1991|
|Matt Skilbeck||Frederick Pyne||1989|
|Sam Pearson||Toke Townley||1984|
|Peggy Skilbeck||Jo Kendall||1973|
|Marian Rosetti||Debbi Blythe (1987 onwards)|
Gail Harrison (until 1976)
|1973 (recurring until 1988)|